After facing down nuclear Armageddon, Crypto finds himself semi-retired and sinning it up in Las Paradiso in the funked-out seventies in Destroy All Humans!™ Path of the Furon. However, when Nexo Cyborg Clones from his home planet attack, Crypto is swept up in a conspiracy that unravels his groovy new way of life on Earth and threatens the very survival of his entire race.

To stop the conspiracy before it's too late, Crypto embarks on a journey of Enlightenment and Destruction, and with the help of an ancient alien Kung Fu master, learn new powers in order to defeat his most difficult enemy yet—his own kind.

• Devastating mental abilities: Embark on the Path of Enlightenment to learn devastating new mental powers from an ancient alien Kung-Fu master. Freeze time and manipulate the world around you with your psychokinetic abilities, hypnotize humans to do your bidding, or snatch their bodies to mingle with the locals.
• Unworldly arsenal: Battle enemies with a devastating arsenal of alien weaponry. Old favorites like the Zap-O-Matic and Anal Probe are back with next-gen upgrades, while new weapons like the Black Hole Gun and the Venus Human Trap let you wreak havoc in new and exciting ways.
• Next-gen UFO: Tight handling, smooth ride, fine Corinthian leather, and lots of guns is how Crypto rolls. Take to the skies and wreak havoc from above with new weapons like the Plasma Cannon and the Tornadotron, or engage in air-to-air combat with the new "fire-and-fugetaboutit" Seeker Drones. 
• High-fidelity destruction: Manipulate or destroy anything in the world. Create disaster movie-level destruction with advanced multi-stage destruction capabilities, collateral damage, chain reactions, and advanced physics. Lay waste to entire cities, creating panic in the streets.
• Open-world play: Go anywhere at any time in an open world mission structure. Explore five huge open environments without ever leaving the game world, or take on a variety of side missions and mini-games.
• Multiplayer modes: Destroy All Humans together through a variety of co-op and adversarial multiplayer modes.

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